Juvéderm™ / Juvéderm™ Ultra Plus
Juvéderm™ injectables are a colorless hyaluronic acid gel with a unique manufacturing process that provides a high concentration of cross-linked hyaluronic acid for long-lasting results. Hyaluronic acid is a naturally occurring sugar found in the human body. The role of a hyaluronic acid in the skin is to deliver nutrients, hydrate the skin by holding in water, and to act as a cushioning agent. Juvéderm™ injectable gel is available in two formulations— Juvéderm™ Ultra for versatility in contouring and volumizing facial wrinkles and folds, and Juvéderm™ Ultra Plus, a more robust formulation for volumizing and correcting deeper folds and wrinkles. This allows your healthcare professional to tailor treatment to meet your unique needs.


Procedure: Juvéderm™ is injected into facial tissue, mid to deep dermis, for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds). Juvéderm™ smoothes wrinkles and folds, especially around the nose and mouth. It also creates a smooth consistency gel that flows easily into the skin and provides a smooth, natural look and feel—so everyone will notice (but no one will know)!
Effectiveness: Juvéderm™ injectable gel is the first FDA-approved hyaluronic acid dermal filler proven safe and effective in persons of color.
Length: Quick and easy procedure: Juvéderm™ injectable gel is a nonsurgical physician-administered treatment that requires no allergy skin test and minimal recovery or downtime. The procedure takes approximately 30 minutes and the results are prompt. Anesthesia: When treating wrinkles, pain relief is usually not needed, but can be easily achieved Side-Effects.
Risks: Most side effects are mild or moderate in nature, and their duration is short lasting (7 days or less). The most common side effects include but are not limited to temporary injection site reactions such as: redness, pain/tenderness, firmness, swelling, lumps/bumps, bruising, itching, and discoloration. Recovery: Immediately after the treatment the treatment area can be slightly swollen and red. This is a normal result of the injection, and generally goes away within 72 hours.
Results: How long the effect of Juvéderm™ treatment lasts is very individual. It depends on many factors, such as the structure of the skin, life style and age, as well as the degree of perfection desired by the individual.
Frequently Asked Questions:
What does JUVÉDERM™ do?
Juvéderm™ injectable gel temporarily adds volume to facial tissue and restores a smoother appearance to the face.
What is JUVÉDERM™ indicated for?
Juvéderm™ Ultra and Juvéderm™ Ultra Plus injectable gels are indicated for injection into the mid to deep dermis (below the outer layer of skin) for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds (the creases running from the bottom of your nose to the corners of your mouth, aka smile lines or parentheses).
Why does JUVÉDERM™ come in two formulations?
Juvéderm™ injectable gel is available in two formulations to allow your healthcare professional to tailor treatment to your unique needs. Juvéderm™ Ultra provides versatility in contouring and volumizing facial wrinkles and folds. Juvéderm™ Ultra Plus is a more robust formulation for volumizing and correcting deeper folds and wrinkles.
How is JUVÉDERM™ injectable gel different from BOTOX® Cosmetic?
Juvéderm™ injectable gel is a “next-generation” hyaluronic acid dermal filler that provides volume and is used to treat wrinkles and folds resulting from a loss of volume beneath the surface of the skin such as perioral lines and nasolabial folds (lines around your mouth and nose). Juvéderm™ restores your skin's volume for a smooth, natural look and feel. BOTOX® Cosmetic is not a filler. BOTOX® Cosmetic relaxes muscle activity and is used to treat moderate to severe lines caused by the dominant frown muscles between the eyebrows (the glabellar area). This allows the two vertical lines between the brows, often referred to as the “11,” to temporarily diminish for a smoother appearance. For important safety information about BOTOX® Cosmetic, see below.
What is hyaluronic acid?
Hyaluronic acid is a naturally occurring substance found in all mammals that helps to hydrate and add volume to your skin. In addition to its use as an aesthetic treatment, hyaluronic acid has also been used for more than 20 years for injection into arthritic joints to aid movement as well as for eye surgeries and wound repair.
What is cross-linked hyaluronic acid?
“Uncross-linked” hyaluronic acid in its natural form is in a liquid state. “Cross-linking” is the process through which hyaluronic acid is made into a gel product that can be injected into the skin for long-lasting results.
Is treatment with JUVÉDERM™ injectable gel painful?
Injections may cause some discomfort during and after the injection. The smooth consistency gel of Juvéderm™ allows your doctor to administer it easily and smoothly. And, Juvéderm™ is injected directly into the skin using a fine needle to reduce injection discomfort. Your doctor may choose to numb (anesthetize) the treatment area to further minimize discomfort.
What kind of doctor can provide treatment with JUVÉDERM™ injectable gel?
Any authorized healthcare professional can administer Juvéderm™ injectable gel, but dermatologists, plastic surgeons, ophthalmologists, otolaryngologists (ear, nose, and throat doctors), or physicians specializing in cosmetic procedures are generally more experienced. Click here to find an experienced doctor near you.
Does the correction last forever?
No. Correction is temporary; therefore, touch-up injections as well as repeat injections are usually needed to maintain optimal corrections.
Can people with different skin tones/colors be treated with JUVÉDERM™?
Yes. In fact, Juvéderm™ injectable gel is the first FDA-approved hyaluronic acid dermal filler that has proven its safety and effectiveness in persons of color. Studies with Juvéderm™ showed no increased risk of hyperpigmentation or hypertrophic scarring in patients of color.
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